Point: high-sensitive troponin assays – a valuable tool for astute physicians
نویسندگان
چکیده
منابع مشابه
Sensitive cardiac troponin assays: sense and sensibility.
To meet the criteria defined in the universal definition of acute myocardial infarction (AMI), sensitive assays for cardiac troponins I and T have recently been introduced into clinical medicine. Such assays are commonly understood to have a detection limit ,99th percentile of a reference population and a total imprecision at the 99th percentile ≤10%. The analytical performance of these assays,...
متن کاملHigh-sensitive cardiac troponin T
Cardiac troponin is the preferred biomarker for the diagnosis of acute myocardial infarction (AMI). The recent development of a high-sensitive cardiac troponin T (hs-cTnT) assay permits detection of very low levels of cTnT. Using the hs-cTnT assay improves the overall diagnostic accuracy in patients with suspected AMI, while a negative result also has a high negative predictive value. The gain ...
متن کاملEarly diagnosis of myocardial infarction with sensitive cardiac troponin assays.
BACKGROUND The rapid and reliable diagnosis of acute myocardial infarction is a major unmet clinical need. METHODS We conducted a multicenter study to examine the diagnostic accuracy of new, sensitive cardiac troponin assays performed on blood samples obtained in the emergency department from 718 consecutive patients who presented with symptoms suggestive of acute myocardial infarction. Cardi...
متن کاملClinical performance of two highly sensitive cardiac troponin I assays.
BACKGROUND The aim of this study was to compare the clinical performance of 2 sensitive cTnI assays with 10% CV imprecision below the 99th percentile upper reference limit. METHODS We measured cardiac troponin and N-terminal pro-brain natriuretic peptide (NT-proBNP) concentrations in a random sample of the Global Use of Strategies To Open Occluded Coronary Arteries (GUSTO) IV cohort (n = 1251...
متن کاملHigh-sensitivity cardiac troponin assays: isn't it time for equality?
There are abundant data that women who present with acute coronary events are less frequently diagnosed and have worse outcomes than men (1, 2 ). Part of the problem may be that women are less apt to manifest increased biomarkers when they present and perhaps for that reason, often receive less aggressive guidelinemandated care (3, 4 ). It may be that the reason for this is that women have lowe...
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ژورنال
عنوان ژورنال: Emergency Care Journal
سال: 2013
ISSN: 1826-9826
DOI: 10.4081/ecj.2013.e15